Tetrahydrocannabinol THC and Cannabidiol CBD
Cannabinoids as Antioxidants and Neuroprotectants United States Patent #6630507
AbstractCannabinoids have been found to have antioxidantproperties, unrelated to NMDA receptor antagonism. This new foundproperty makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. Thecannabinoids are found to have particular application asneuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia. Nonpsychoactivecannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactivecannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful asneuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH.sub.3, andCOCH.sub.3. ##STR1##
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC)
BRAIN INJURIES
How hash became a smash in brain trauma research
MAPS: How hash became a smash in brain trauma research
MAPS: How hash became a smash in brain trauma research
Synthetic Marijuana Helps Trauma Patients
medical marijuana, medical marijuana canada, compassion club,medical cannabis, medical marijuana vancouver – SyntheticMarijuana Helps Trauma Patients
medical marijuana, medical marijuana canada, compassion club,medical cannabis, medical marijuana vancouver – SyntheticMarijuana Helps Trauma Patients
NEUROPROTECTANT
Marijuana Protects Your Brain
art-mjbrain.html
art-mjbrain.html
The neuroprotective effect of cannabinoids in a rat model of Parkinson’s disease
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http://www.medscape.com/medline/abstract/17196181
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http://www.medscape.com/medline/abstract/17196181
Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-THC
Unbound MEDLINE | Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-Tetrahydrocannabinol in a Rat Model of Glaucoma. Journal article
Unbound MEDLINE | Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-Tetrahydrocannabinol in a Rat Model of Glaucoma. Journal article
Blue Cheese
Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
Unbound MEDLINE | Neuroprotective effect of (-)Delta9-tetrahydrocannabinol andcannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite. Journal article
Unbound MEDLINE | Neuroprotective effect of (-)Delta9-tetrahydrocannabinol andcannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite. Journal article
Neuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells
Unbound MEDLINE | Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts duringneuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells. Journal article
Unbound MEDLINE | Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts duringneuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells. Journal article
Cannabidiol has a cerebroprotective action
Unbound MEDLINE | Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. Journal article
Unbound MEDLINE | Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. Journal article
Cannabidiol but not Delta(9)-THC has a neuroprotective effectwithout the development of tolerance..
Unbound MEDLINE | Repeated treatment with cannabidiol but not Delta(9)-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance. Journal article
Unbound MEDLINE | Repeated treatment with cannabidiol but not Delta(9)-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance. Journal article
Delta(9)-THC) prevents cerebral infarction
Unbound MEDLINE | Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Journal article
Unbound MEDLINE | Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Journal article
Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
Unbound MEDLINE | Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Journal article
Unbound MEDLINE | Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Journal article
Cannabis and Neuroprotection
AAMC: Cannabis and Neuroprotection
AAMC: Cannabis and Neuroprotection
Neuroprotection by Delta 9-THC against Ouabain-Induced In Vivo Excitotoxicity
Neuroprotection by {Delta}9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity — van der Stelt et al. 21 (17): 6475 — Journal of Neuroscience
Neuroprotection by {Delta}9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity — van der Stelt et al. 21 (17): 6475 — Journal of Neuroscience
Jack Herer
Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures
Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures — Nagayama et al. 19 (8): 2987 — Journal of Neuroscience
Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures — Nagayama et al. 19 (8): 2987 — Journal of Neuroscience
Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism
British Journal of Pharmacology
British Journal of Pharmacology
The use of cannabinoids in MS: is it evidence based?
http://www.ukcia.org/research/UseOfC…denceBased.pdf
http://www.ukcia.org/research/UseOfC…denceBased.pdf
Neurons on Cannabinoids: Dead or Alive?
http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf
http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf
Cannabinoids and Brain Injury: Therapeutic Inplications
http://www.ukcia.org/research/Cannab…rainInjury.pdf
http://www.ukcia.org/research/Cannab…rainInjury.pdf
Cannabidiol and delta 9-THC are neuroprotective antioxidants
http://www.ukcia.org/research/Neurop…tioxidants.pdf
http://www.ukcia.org/research/Neurop…tioxidants.pdf
Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotectiveantioxidants
Cannabidiol and (−Δ9-tetrahydrocannabinol areneuroprotective antioxidants
Cannabidiol and (−Δ9-tetrahydrocannabinol areneuroprotective antioxidants
Endocannabinoids in the retina: From marijuana to neuroprotection.
Unbound MEDLINE | Endocannabinoids in the retina: From marijuanato neuroprotection. Journal article
Unbound MEDLINE | Endocannabinoids in the retina: From marijuanato neuroprotection. Journal article
Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders.
Unbound MEDLINE | Cannabidiol in medicine: a review of itstherapeutic potential in CNS disorders. Journal article
Unbound MEDLINE | Cannabidiol in medicine: a review of itstherapeutic potential in CNS disorders. Journal article
OG Kush
Cannabidiol: a promising drug for neurodegenerative disorders?
Unbound MEDLINE | Cannabidiol: a promising drug forneurodegenerative disorders? Journal article
Unbound MEDLINE | Cannabidiol: a promising drug forneurodegenerative disorders? Journal article
Cannabis TV Documentaries:
Links:
Peer Reviewed Research:
http://montanabiotech.com/2011/09/16/brain-injuries-and-the-neuroprotectant-properties-and-therapeutic-effects-of-medical-cannabis-marijuana-cannabinoids-tetrahydrocannabinol-thc-and-cannabidiol-cbd/
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